Mouse Monoclonal Antibody Production

Achieve high-affinity, high-specificity antibodies with abm’s Mouse Monoclonal Antibody Production Service. We combine expert immunization strategies, precise antigen design, and advanced screening technologies to deliver reliable and reproducible results tailored to your research needs.

Our proprietary immunization protocols and thoughtful mouse strain selection are key to generating robust monoclonal antibodies. Special attention is given to antigen and peptide design, ensuring your antibody recognizes conformational changes in the native protein across a variety of conditions.

Whether for diagnostics, therapeutics, or basic research, trust abm to provide top-tier monoclonal antibodies backed by scientific precision and decades of experience.


Service Details

Core Services
Service Name Description Cat. No. Unit Price
Complete Package
with peptide production
  1. Peptide antigen production
  2. Immunization (5 mice/antigen) and Sera Testing by ELISA
  3. Fusion and Colony Screening
  4. Subcloning, Colony Expansion and Freezing (2 clones)
  5. (Optional) Antibody Purification by Protein A/G 
C080 1 Service Starting from $8,900
Complete Package
with protein production
  1. Protein antigen production
  2. Immunization (5 mice/antigen) and Sera Testing by ELISA
  3. Fusion and Colony Screening
  4. Subcloning, Colony Expansion and Freezing (2 clones)
  5. (Optional) Antibody Purification by Protein A/G 
C487 1 Service Starting from $9,400
Standard Package
without antigen production
  1. Immunization (5 mice/antigen) and Sera Testing by ELISA
  2. Fusion and Colony Screening
  3. Subcloning, Colony Expansion and Freezing (2 clones)
  4. (Optional) Antibody Purification by Protein A/G 
C087 1 Service Starting from $7,900
Amount of antigen to submit for Standard Package Service:
For peptide antigens, please submit at least 2mg. For protein antigens, please submit at least 5mg with concentrations of 0.5-1.0mg/ml.

Additional Info

  • Customers can provide a peptide antigen or a ready-to-inject antigen for monoclonal antibody production. When using a peptide antigen supplied by the customer, an additional charge of $250.00 is applied for KLH conjugation.
  • Customers have the option to start or stop the project from any stages of the mouse monoclonal antibody generation service. Customers will be responsible for the material and labour cost incurred thus far should early termination be requested.

Customer Review:

"I am a fan of abm: great product quality, great price, great rewards and great experience."

Dr. Vincent Emond, Centre de recherche du CHU de Québec CHUL

FAQs

What is the shortest length peptide that you can produce an antibody against?
To produce an antibody that has specificity and affinity at acceptable levels, we require a minimum of 20 amino acids.
Can you produce an antibody against a native protein?
Yes, however to guarantee the antibody is effective against the native protein purified native protein must be used for immunization. Recombinant protein or peptide extracts can also be used to immunize, but we cannot guarantee these will be effective against the native protein due to folding and other conformational issues. We only guarantee that the immunized protein (native or recombinant) or peptide will be recognized by the produced antibody.
What is the isotype of antibody your production produces?
Our process mainly results in IgG2a and IgG2b antibodies.
What concentration and amount of antigen is required for production if I am supplying the protein/peptide?
For peptide antigens we require at least 2mg, while if it is a protein 5mg with concentrations of 0.5-1.0mg/ml are acceptable.
Do you deliver the Hybridoma cells along with the custom antibody?
Please inquire with quotes@abmgood.com
What information do I need to provide to obtain a quote?
Please provide: 1) The peptide antigen design 2) Mouse monoclonal or Polyclonal Antibody Production? 3) Are you looking for the standard service or complete service? Please email this information to quotes@abmgood.com

Citations

01 Ko, FC et al. "PKA-induced dimerization of the RhoGAP DLC1 promotes its inhibition of tumorigenesis and metastasis." Nat Commun 4:1618 (2013). PubMed: 23511482