ROCK Inhibitor Y-27632

Cat. No.

TM131

Unit

10 mg

Price

$168.00

Cat. No.

TM131

Name

ROCK Inhibitor Y-27632

Description

ROCK Inhibitor Y-27632 is a potent and selective small molecule inhibitor of Rho-associated coiled-coil containing protein kinase (ROCK). It is commonly used in cell culture to promote cell survival, enhance cell proliferation, and maintain the undifferentiated state in various cell types, particularly in stem cell research and tissue engineering applications.

Y-27632 is an ATP-competitive inhibitor of ROCK-I and ROCK-II. It also prevents apoptosis induced by isolation in mouse prostate stem or progenitor cells.

Chemical Properties
Molecular Weight	247.34
Formula	C₁₄H₂₁N₃O
Cas No.	146986-50-7
Relative Density	1.136 g/cm³
Solubility	H₂O: insoluble 10% DMSO+90% Saline: 2.47 mg/mL (9.99 mM). For In vivo, add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. DMSO: 45 mg/mL (181.94 mM)

Unit

10 mg

Storage Condition

Keep away from direct sunlight. In powder form, store at -20°C. In solvent form, store at -80°C for 1 year.

Material Citation

If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. TM131

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