Neuroscience Collection
abm’s 3D mini-brain organoids are advanced, self-organizing human brain models generated using proprietary culture media that directly overcome the limitations of traditional 2D cultures, which fail to recapitulate complex cell-to-cell interactions. This powerful platform can significantly reduce or even replace reliance on costly animal studies.
abm is uniquely positioned as a global leader with one of the largest and most versatile mini-brain portfolios available, including models derived from human, rat, and mouse tissues, as well as disease-specific mini-brains for Alzheimer’s, Parkinson’s, Huntington’s disease, multiple sclerosis, and various cancers.
Mini Brain Organoids - Healthy & Diseased
Figure 1. Functional characterization of NSC-derived neurons within Human Mini Brain Organoids. Human Mini Brain Organoids (NSC Derived) (Cat. No. R0001) contain functional, differentiated neurons that (A) express the neuron-specific marker βIII-tubulin (TUJ1) and the glial marker GFAP, (B) exhibit current-induced action potentials as measured by patch-clamp electrophysiology, and (C) form mini brain–like 3D structures when cultured in 3DCeMatrix™ (Cat. No. TM076). Panels (D) and (E) show Mouse and Rat Mini Brain Organoids (NSC Derived), respectively, Cat. No. R1000 and Cat. No. R2000, for comparative visualization of species-specific morphology in culture.
Product List
| Product Name | Cat. No. | Description | Quantity | Price |
|---|---|---|---|---|
| Healthy Model | ||||
| Human Mini Brain Organoids – NSC Derived | R0001 | Ready-to-use 3D human brain organoids derived from neural stem cells. These organoids mimic key features of early neurodevelopment and offer a robust, scalable platform for modeling neurological disease and testing therapeutic compounds. | 10 Organoids/Vial | $999.00 |
| Mouse Mini Brain Organoids – NSC Derived | R1000 | Ready-to-use 3D mouse brain organoids derived from neural stem cells. These organoids mimic key features of early neurodevelopment and offer a robust, scalable platform for modeling neurological disease and testing therapeutic compounds. | 10 Organoids/Vial | $999.00 |
| Rat Mini Brain Organoids – NSC Derived | R2000 | Ready-to-use 3D rat brain organoids derived from neural stem cells. These organoids mimic key features of early neurodevelopment and offer a robust, scalable platform for modeling neurological disease and testing therapeutic compounds. | 10 Organoids/Vial | $999.00 |
| Alzheimer’s Disease Model | ||||
| Human Mini Brain Organoids – NSC Derived, Alzheimer’s | R0002 | NSC-derived 3D human mini brain organoids engineered to model key pathological features of Alzheimer’s disease, ideal for studying neurodegeneration and screening potential therapeutics. | 10 Organoids/Vial | $999.00 |
| Parkinson’s Disease Model | ||||
| Human Mini Brain Organoids – NSC Derived, Parkinson’s | R0003 | NSC-derived 3D human mini brain organoids engineered to model key pathological features of Parkinson’s disease, ideal for studying neurodegeneration and screening potential therapeutics. | 10 Organoids/Vial | $999.00 |
| Huntington’s Disease Model | ||||
| Human Mini Brain Organoids – NSC Derived, Huntington’s | R0004 | NSC-derived 3D human mini brain organoids engineered to model key pathological features of Huntington’s disease, ideal for studying neurodegeneration and screening potential therapeutics. | 10 Organoids/Vial | $999.00 |
Brain Tumor–Derived Spheroids (Oncology Models)
3D spheroid models derived from brain tumors cell lines, providing a physiologically meaningful platform for studying tumor behavior, drug response, and therapeutic resistance in glioblastoma, astrocytoma, and other CNS cancers.
Product List
| Product Name | Cat. No. | Description | Quantity | Price |
|---|---|---|---|---|
| Oncology Model | ||||
| Human Glioblastoma Spheroids – Cell Line Derived | R1900 | 3D patient-relevant glioblastoma spheroids that recapitulate the invasive, heterogeneous nature of GBM tumors. These physiologically meaningful oncology models support studies in tumor biology, drug resistance, screening of anti-cancer compounds, and evaluation of targeted therapeutics. | 10 Spheriods/Vial | $999.00 |
| Human Astrocytoma Spheroids – Cell Line Derived | R1901 | 3D astrocytoma spheroids derived from tumor cells, capturing the morphology, growth characteristics, and molecular features of astrocytic cancers. An ideal platform for investigating tumor progression, testing novel therapeutics, and profiling drug responses in a human-relevant model. | 10 Spheriods/Vial | $999.00 |