SB 202190
| Cat. No. | G7202 |
| Name | SB 202190 |
| Description |
SB 202190 is a potent, selective, ATP-competitive inhibitor of the p38 MAP kinase (MAPK14/11) pathway, with strong preference for the α and β isoforms. By blocking p38 MAPK activity, SB 202190 effectively suppresses downstream signaling cascades involved in cellular stress response, inflammation, apoptosis, and differentiation. In stem cell and iPSC research, SB 202190 is commonly used to support reprogramming, enhance pluripotency, and control lineage-specific differentiation, particularly in neuronal and cardiac cell models. It is also widely applied in studies of immune regulation, cytokine signaling, and disease modeling.
Key Features:
Applications:
Specifications:
|
| Unit | 10 mg |
| Usage |
Typical iPSC use: 5–10 µM (optimization required) |
| Storage Condition | Store powder at –20 °C, protected from light. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. G7202 |