Lenti-HPV E6/E7 (Puro) Virus, High Titer
| Cat. No. | LV617 |
| Name | Lenti-HPV E6/E7 (Puro) Virus, High Titer |
| Unit | 2 x 100 µl |
| Unpacking and Storage Instructions |
Lentiviruses are shipped with dry ice. For long term storage, it is recommended to store the viruses at -80°C in small aliquots to avoid repeated freeze-thaw cycles. |
| Description |
High Titer (109 IU/ml) Recombinant Lentivirus expressing the HPV-16 E6/E7 gene. |
| Application |
Cell immortalization of keratinocytes. |
| Expression System Type | Lentivirus |
| Note |
Not for resale without prior written consent of abm. |
| Caution |
This product is distributed for laboratory research only. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. LV617 |
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- Balducci, L et al. "Immortalization of human adipose-derived stromal cells: production of cell lines with high growth rate, mesenchymal marker expression and capability to secrete high levels of angiogenic factors" Stem Cell Research & Therapy 3:63 (2014). DOI: 10.1186/scrt452. PubMed: 24887516. Application: Immortalization.
- Calvo, F et al. "Isolation and Immortalization of Fibroblasts from Different Tumoral Stages" Bio-protocol 4(7):e1097 (2014). Application: Immortalization.
- He, et al. "The Hippo/YAP pathway interacts with EGFR signaling and HPV oncoproteins to regulate cervical cancer progression" EMBO Molecular Medicine 11:1426-1449 (2015). DOI: 10.15252/emmm.201404976.
- Coleman, S et al. "A Homolog Pentameric Complex Dictates Viral Epithelial Tropism, Pathogenicity and Congenital Infection Rate in Guinea Pig Cytomegalovirus" PLoS Pathog 12.7:e1005755 (2016). DOI: 10.1371/journal.ppat.1005755. Application: Immortalization.
- Lee, Y., Berríos-Vázquez, G., Maes, R. K., Kiupel, M., Desmarets, L. M. B., Nauwynck, H. J., & Soboll Hussey, G. (2023). Development of immortalized feline respiratory epithelial cells in an air-liquid-interface culture system for feline herpesvirus-1 study. Virus Research, 326, 199063. https://doi.org/10.1016/j.virusres.2023.199064
- He, C., Lv, X., Liu, J., Ruan, J., Chen, P., Huang, C., Angeletti, P. C., Hua, G., Moness, M. L., Shi, D., Dhar, A., Yang, S., Murphy, S., Montoute, I., Chen, X., Islam, K. N., George, S., Ince, T. A., Drapkin, R., … Wang, C. (2024). HPV-YAP1 oncogenic alliance drives malignant transformation of fallopian tube epithelial cells. EMBO Reports, 25(10), 4542–4569. https://doi.org/10.1038/s44319-024-00233-3
- Huang, C., Lv, X., Chen, P., Liu, J., He, C., Chen, L., Wang, H., Moness, M. L., Dong, J., Rueda, B. R., Davis, J. S., & Wang, C. (2022). Human papillomavirus targets the YAP1-LATS2 feedback loop to drive cervical cancer development. Oncogene, 41(30), 3761–3777. https://doi.org/10.1038/s41388-022-02390-y
- Jenkins, L., Jungwirth, U., Avgustinova, A., Iravani, M., Mills, A., Haider, S., Harper, J., & Isacke, C. M. (2022). Cancer-Associated Fibroblasts Suppress CD8+ T-cell Infiltration and Confer Resistance to Immune-Checkpoint Blockade. Cancer Research, 82(16), 2904–2917. https://doi.org/10.1158/0008-5472.can-21-4141
- Choi, K. Y., El-Hamdi, N., & McGregor, A. (2022). Endothelial Cell Infection by Guinea Pig Cytomegalovirus Is a Lytic or Persistent Infection Depending on Tissue Origin but Requires Viral Pentamer Complex and pp65 Tegument Protein. Journal of Virology, 96(17), e00831-22. https://doi.org/10.1128/jvi.00831-22
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