Recombinant Human IL28B (IFNL3)
| Cat. No. | Z101285 |
| Name | Recombinant Human IL28B (IFNL3) |
| Description | Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway. |
| Organism | Human (H. sapiens) |
| Unit quantity | 10 µg |
| Family | IL-10/Interferon Family |
| Tag | Tag Free |
| Aliases | IFN-lambda-3, IFN-lambda-4, IL-28B, IL-28C, IL28B, IL28C |
| Gene Symbol | IFNL3 |
| Gene ID | 282617 |
| Accession Number | Q8IZI9 |
| Source | CHO cells |
| Species | Human (H. sapiens) |
| Appearance | Lyophilized Powder |
| Molecular Weight | 23 kDa |
| Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method. |
| Purity | >95% as determined by SDS-PAGE |
| Formulation | Recombinant Human Interleukin-28B was lyophilized from a 0.2 μm filtered PBS solution pH 7.4. |
| Function | The activity was determined by a WISH cell viral resistance assay with a linear range of 4-20 ng/mL. |
| Reconstitution | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Storage | The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
| Usage | For research use only. Not for diagnostic or therapeutic use. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z101285 |
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The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
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