dCas9-DNMT3A Lentiviral Vector
| Cat. No. | K091 |
| Name | dCas9-DNMT3A Lentiviral Vector |
| Unit | 10 µg |
| Description |
Lentiviral vector expressing dCas9 (D10A and H840A) fused to the DNA methyltransferase (DNMT3A) domain. The DNMT3A domain facilitates the process of methylation leading to transcriptional down-regulation. By using specific sgRNAs, the dCas9-DNMT3A can be targeted to a genomic region allowing for epigenetic control over the expression of almost any gene of interest. |
| Applications |
CRISPR epigenetic modification. |
| Storage Condition | -20°C or below. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. K091 |
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