dCas9-DNMT3A Lentivirus
| Cat. No. | K092 |
| Name | dCas9-DNMT3A Lentivirus |
| Unit | 4 x 500 µl |
| Description |
Lentivirus expressing dCas9 (D10A and H840A) fused to the DNA methyltransferase (DNMT3A) domain. The DNMT3A domain facilitates the process of methylation leading to transcriptional down-regulation. By using specific sgRNAs, the dCas9-DNMT3A can be targeted to a genomic region allowing for epigenetic control over the expression of almost any gene of interest |
| Applications |
CRISPR epigenetic modification. |
| Titer | 107 IU/mL |
| Storage Condition | Lentiviruses are shipped with dry ice. For long term storage, it is recommended to store the viruses at -80°C in small aliquots to avoid repeated freeze-thaw cycles. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. K092 |
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