dCas9-KRAB Lentiviral Vector

Cat. No.
K203
Unit
10 µg
Price
$212.00
Cat. No. K203
Name dCas9-KRAB Lentiviral Vector
Unit 10 µg
Description

Lentiviral vector expressing dCas9 (D10A and H840A) fused to the KRAB (Krüppel-associated box) domain, which represses gene expression by binding to the promoter region and blocking transcription. By using specific sgRNAs, the dCas9-KRAB can be targeted to a promoter region allowing for repression of almost any gene of interest.

Applications

CRISPR gene repression.

Storage Condition -20°C or below.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. K203
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  • Dai, X., Chen, X., Hakizimana, O., & Mei, Y. "Genetic interactions between ANLN and KDR are prognostic for breast cancer survival" Oncology Reports. : (2019).
  • Dai, X., Chen, X., Hakizimana, O., & Mei, Y. (2019). Genetic interactions between ANLN and KDR are prognostic for breast cancer survival. Oncology Reports. https://doi.org/10.3892/or.2019.7332
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