Anti-Cas9 Antibody
| Cat. No. | Y300079 |
| Name | Anti-Cas9 Antibody |
| Category | Monoclonal Antibodies |
| Application | WB,ELISA |
| Application Info |
Working dilution must be determined by the user. |
| Raised In | Mouse |
| Clonality | Monoclonal |
| Reactivity | Other |
| Description |
Anti-Cas9 Antibody is an antibody against Cas9, an essential RNA-guided DNA endonuclease observed originally in Streptococcus pyogene among other bacteria and archaea and a component of an adaptive microbial immune system that provides acquired immunity against foreign viruses and plasmids. Cas9 endonuclease is used to cleave double-stranded DNA directed by a short engineered guide-RNA (gRNA), leading to site-directed double strand breaks (DSB) in DNA submstrate. Thus, the CRISPR Cas9 system (clustered regularly interspaced short palindromic repeat CRISPR-associated protein 9) is the latest RNA-guided, endonuclease tool in genome editing which allows for very specific genomic disruption and replacement. |
| Immunogen | Recombinant fragment corresponding to Cas9 endonuclease from Streptococcus pyogenes. |
| Isotype | IgG1 |
| Concentration | 100 μg / 100 μl |
| Recommended Dilutions | Working dilution must be determined by the user. |
| Storage Buffer | PBS, pH 7.4 with 0.02% sodium azide. |
| Storage Condition |
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Other |
| Purity | Affinity purified from ascites fluid. |
| Guarantee |
abm guarantees that all our Anti-Cas9 Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Y300079 |