SensiStain™ Anti-BCL2 Antibody
Cat. No.
HY000014
Unit
0.1 ml
Price
$156.00
| Cat. No. | HY000014 |
| Name | SensiStain™ Anti-BCL2 Antibody |
| Clone | IHC514 |
| Category | IHC Antibodies |
| Gene Name | BCL2 |
| Gene Full Name | B-cell CLL/lymphoma 2 |
| Alias | Bcl-2, BCL-2, PPP1R50 |
| Accession Number | NM_000633 |
| Application | ELISA, IHC |
| Raised In | Mouse |
| Clonality | Monoclonal |
| Reactivity | Human |
| Description |
B-Cell Lymphoma 2 (BCL2) is involved in regulation of cell apoptosis by controlling mitochondrial permeability and release of cytochrome c. It also has critical roles in normal cell physiology related to neuronal activity, autophagy, calcium handling, mitochondrial dynamics, and energetics. BCL2 overexpression has been shown to promote cell survival by suppressing apoptosis, and is found to be correlated with poor disease prognosis in breast, prostate, ovarian, endometrial, and colon cancers. |
| Immunogen | Recombinant Protein |
| Isotype | IgG1 |
| Uniprot Number | P10415 |
| Recommended Dilutions |
1:50-1:200 |
| Storage Buffer | Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
| Storage Condition |
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. HY000014 |
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