SensiStain™ Anti-PD-L1 Antibody
| Cat. No. | HY000271 |
| Name | SensiStain™ Anti-PD-L1 Antibody |
| Clone | IHC411 |
| Category | IHC Antibodies |
| Gene Name | PD-L1 |
| Application | ELISA, IHC |
| Raised In | Rabbit |
| Clonality | Monoclonal |
| Reactivity | Human |
| Description |
Programmed Death-Ligand 1 (PD-L1), CD274, or B7 Homolog 1 (B7-H1), is a transmembrane protein involved in suppressing the immune system and rendering tumour cells resistant to lysis through binding of the Programmed Death-1 (PD-1) receptor. Overexpression of PD-L1 may allow cancer cells to evade the actions of the host immune system. In renal cell carcinoma, upregulation of PD-L1 has been linked to increased tumour aggressiveness and risk of death. |
| Immunogen | Recombinant Protein |
| Isotype | IgG |
| Uniprot Number | Q9NZQ7 |
| Recommended Dilutions |
1:50-1:200 |
| Storage Buffer | Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
| Storage Condition |
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. HY000271 |