SensiStain™ Anti-Perforin Antibody
| Cat. No. | HY500104 |
| Name | SensiStain™ Anti-Perforin Antibody |
| Clone | IHC646 |
| Category | IHC Antibodies |
| Gene Name | Perforin |
| Application | ELISA, IHC |
| Raised In | Mouse |
| Clonality | Monoclonal |
| Reactivity | Human |
| Description |
Perforin, a pore-forming protein found in the granules of cytotoxic T-lymphocytes and natural killer cells, functions to enable granzymes to enter the target cells and activate apoptosis. It has been suggested that perforin plays a role in alloimmunity, being involved in both the cytolytic process of rejection as well as downregulation of the T-cell mediated responses associated with the alloimmune response. Perforin-mediated cytotoxicity has also been linked to a number of autoimmune diseases. |
| Immunogen | Recombinant Protein |
| Isotype | IgG2c |
| Uniprot Number | P14222 |
| Recommended Dilutions |
1:50-1:200 |
| Storage Buffer | Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
| Storage Condition |
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. HY500104 |