Recombinant Human TRAIL (TNFSF10) (E. coli)

Cat. No.

Z101755

Unit

Price

$200.00

Cat. No.	Z101755
Name	Recombinant Human TRAIL (TNFSF10) (E. coli)
Description	A cytotoxic protein, TRAIL initiates apoptosis in tumor cells by binding the death-signalling receptors; DR4 and DR5. In its active conformation, TRAIL forms homotrimers. TRAIL transcripts have been shown to be constitutively expressed in a variety of human tissues. There are five known TRAIL receptors: two which transduce apoptotic signals, two which function as decoys to block TRAIL-induced apoptosis and osteoptotegrin.
Organism	Human (H. sapiens)
Unit quantity	10 µg
Family	TNF Super-family
Aliases	APO2L, Apo-2L, CD253, TANCR, TL2, TNLG6A, TRAIL
Gene Symbol	TNFSF10
Gene ID	8743
Accession Number	P50591
Source	E. coli
Species	Human (H. sapiens)
Appearance	Lyophilized Powder
Molecular Weight	19.5 kDa
Endotoxin Level	< 1.0 EU/µg of recombinant protein as determined by the LAL method.
Purity	>95% as determined by SDS-PAGE
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Function	N.A.
Reconstitution	Reconstitute at 20 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin
Storage	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage	For research use only. Not for diagnostic or therapeutic use.
Material Citation	If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z101755

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Cell type: Different cells respond to different growth factors. Choose a growth factor that promotes the growth or differentiation of your target cell type.
Desired outcome: Whether you are studying proliferation, differentiation, or survival, different growth factors will promote different cellular behaviors.
Concentration and formulation: Different experiments may require varying concentrations of growth factors.

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	What is the shelf life and storage condition of this product?
	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.