SensiStain™ Anti-B7-H4 Antibody
| Cat. No. | HY000305 |
| Name | SensiStain™ Anti-B7-H4 Antibody |
| Clone | IHC104 |
| Category | IHC Antibodies |
| Gene Name | B7-H4 |
| Application | ELISA,IHC |
| Raised In | Mouse |
| Clonality | Monoclonal |
| Reactivity | Human |
| Description |
B7-H4 is a glycosylated transmembrane protein of the B7 family. It binds to activated T cells to moderate the T cell responses via cell cycle arrest in the T cell. Reverse signaling can induce either cell cycle arrest or apoptosis in the B7-H4 expressing cell. B7-H4 is up-regulated in several carcinomas in correlation with tumor progression and metastasis. A soluble form of B7-H4 is elevated in the serum of ovarian cancer, renal cell carcinoma, and rheumatoid arthritis patients, also in correlation with advanced disease status. |
| Immunogen | Recombinant Protein |
| Isotype | IgG2b |
| Uniprot Number | Q7Z7D3 |
| Recommended Dilutions |
1:50-1:200 |
| Storage Buffer | Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
| Storage Condition |
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. HY000305 |