SensiStain™ Anti-DUSP4 Antibody
| Cat. No. | HY500219 |
| Name | SensiStain™ Anti-DUSP4 Antibody |
| Clone | IHC491 |
| Category | IHC Antibodies |
| Gene Name | DUSP4 |
| Application | ELISA,IHC |
| Raised In | Mouse |
| Clonality | Monoclonal |
| Reactivity | Human |
| Description |
DUSPs, also known as MAPK phosphatases (MKPs), residues in MAPK P-loops and have been shown to play important roles in regulating the function of the MAPK family. Downregulation or loss of DUSP4 expression has been frequently observed in several malignancies including colorectal cancer, pancreatic cancer, gastric cancer, lung cancer, and breast cancer. It could be a novel drug target since the study has shown the constitutive expression of DUSP4 in cancer cells contributes to enhanced proliferation through escape from apoptosis and cell cycle arrest. |
| Immunogen | Recombinant Protein |
| Isotype | IgG1 |
| Uniprot Number | Q13115 |
| Recommended Dilutions |
1:50-1:200 |
| Storage Buffer | Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
| Storage Condition |
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. HY500219 |