CRISPRa dCas9-VPR Lentiviral Vector
| Cat. No. | K097 |
| Name | CRISPRa dCas9-VPR Lentiviral Vector |
| Unit | 10 µg |
| Description |
Lentiviral vector expressing dCas9 (D10A and H840A) fused to the VPR activator complex (VP64, p65, Rta), which enhances gene expression by recruiting transcription factors. Unlike the dCas9-SAM system, dCas9-VPR doesn't require MS2-modified sgRNAs, simplifying delivery with a single fusion protein encoded in one vector. By using specific sgRNAs, the dCas9-VPR can be targeted to a promoter region allowing for activation of almost any gene of interest. |
| Applications |
CRISPR gene activation. |
| Storage Condition | -20°C or below. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. K097 |
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